Frank Walton was born in Beaver Falls, Pennsylvania on December 25, 1911 and attended Beaver Falls High School. He played  college football at the University of Pittsburgh in 1932-1933 and played for the 1932 Rose Bowl team. He finished his college career by playing in the 1933 College All Star Game.

Frank went on to play professional football as a guard for the Boston Redskins in 1934.

He became head football coach at Beaver Falls High from 1935 to 1940, and was  a coach of the Geneva College football team in 1942.

Frank returned to the Redskins as a player and assistant coach from 1944 to 1946 and after that served as an assistant football coach at Colgate and at West Virginia University. He also coached the Richmond Rebels semipro team. 

Frank Walton battled cancer and passed away on September 22, 1953, at age 41, in Beaver Falls.