Larry Siemering was born in San Francisco on November 24, 1910 and attended Lodi High School and graduated in 1928. Also during this time, he played semi-pro baseball for the Sacramento Stallions. He accepted a baseball scholarship and played football for the University of San Francisco.
Larry played pro football as the center for the Boston Redskins in 1935 and 1936.
After his playing career, he started his coaching career as a high school football coach at Manteca High School and then Stockton High School in the San Joaquin Valley. In 1943, his Stockton team went undefeated.
He next served as an assistant coach and then the head football coach at the University of the Pacific in Stockton, California from 1947 to 1951. In 1949, The Tigers outscored their opponents 575–66 and led the nation in offense. The team was the 15th college team in history to score 500 or more points in a single season. During his four-year tenure at Pacific, Larry's teams went 35–5–3. He then coached at Arizona State University in 1951.
In 1953, Larry was the offensive line coach for the Washington Redskins. He moved on to be the head coach of the Canadian Football League's Calgary Stampeders in 1954. Then Larry came back to high school coaching in 1956, at Santa Cruz High School, where his team went undefeated in 1958.
Larry became the inaugural head coach at Cabrillo College, a two-year community college Aptos, California. He coached there from 1959 to 1965.
Larry Siemering was inducted into the first class of the University of Pacific Athletic Hall of Fame in 1982 and passed away on July 24, 2009, at age 98, in the Watsonville Community Hospital, in Watsonville, California, after a fall at his home. At the time of his death, he was the oldest surviving professional football player.